Does Lisinopril Work? Can it Help Reduce Blood Pressure?

I met with my doctor this week and due to my family history of strokes, plus my own stroke, he wanted to put me on Lisinopril, a blood Medicinepressure medication (Lisinopril is the generic form of the drug Zestril). The simple answer is that it does work for me. The more difficult question is, how long will I be on it and can I improve my health so I don’t need it any longer?

Please allow me to make the point of this article clear before going further. I am not trying to convince anyone that blood pressure is great and life will be just wonderful if you will just take this one little pill. On the contrary. There are real health risks and side effects to any medication. This is more about my journey and how the medicine affected me and my plan to get off the medication with my doctor’s help.

My First Hour on Lisinopril

I picked up my blood pressure medicine in the evening of February 16th, 2018. I followed the instructions for taking my blood pressure with my Omron 7 Series monitor. I sat down at my desk and relaxed while doing some work. Once I felt relaxed, I took my blood pressure. Here are the results:

Readings Before Taking Lisinopril
I took this first blood pressure reading at 11:55pm and it wasn’t too bad, in my opinion. It was 134/85.

Next I set my timer and went back to work. I didn’t change a thing for the next 30 minutes other than taking one dose of a 20MG tablet of Lisinopril.

After the 30 minutes was up I checked my blood pressure for a second time.

Readings after taking Lisinopril
You can see the immediate reduction in my blood pressure to 122/82. That’s pretty great, right?

The last thing I would like to point out is after approximately 19 hours, it looks like the medication starts wearing off and I see a slight rise in my blood pressure reading at 6:46pm. I took my next days dose at about 7:30pm and waited for 1 hour, then took my blood pressure again. My blood pressure dropped back down immediately, as it had the night before.

So, Lisinopril does work for me but that doesn’t mean I’m happy taking it.

The Positives and Negatives

The positive was the immediate reduction in my blood pressure to “normal.” The negative was a little more subtle.

I felt different in the hour immediately after taking the medication. The best way I can describe it was the feeling you get in your head when you took one to many pills of your medication. Another analogy would be if you hadn’t had much to eat all day and you sat down for dinner and had a glass of wine before the meal came out. You would probably start sensing a little “something” and reach for some bread to hopefully ease that feeling, or you might like the feeling and ask for another.

I wouldn’t necessarily list this feeling as negative, as the medication did just help my blood pressure, however, It’s strange to feel a chemical change in your body, especially when it was such a low dose.

My Doctor’s Note/Pass for One Month

This is the more difficult question about how long will I be on Lisinopril.

I received a follow up email from the doctor about my lab results and what he noticed in it. He said at one point that he wanted to put me back on the cholesterol medicine or I would have to get onto a strict diet and workout plan.

I have a scheduled follow up appointment within 2 months and I don’t want to hear the words, “I’m going to have to up your Lisinopril dose and put you on cholesterol medication because you did not make enough healthy changes in your life.”

Ready, Set, GO!

Now, I’m looking at myself in the mirror, or more appropriately, the reflection in my monitor, and asking myself…..”how serious am I about staying off medication and getting off the one prescription I am on?”




14 thoughts on “Does Lisinopril Work? Can it Help Reduce Blood Pressure?”

  1. Hi i dont have blood pressure issues now but i do work with 1 that does have blood pressure problems and he takes medicine for it, sometimes our department which is only a few of us on our shift, will sit and talk with him an such when he asks questions. i can understand on making sure you take the correct medicine for your own body can handle. i hope i helped 🙂

    • I have learned a lot from my Mother and Father, who take more medication. My Mother has had a severe stroke and my father has some heart issues, including two stints, so they have several medications they have to take. My Father is really careful about their medication and watching for negative side effects. He has helped me to become more aware of some of the dangers on medication and the importance of doing what you can to stay off of them.

  2. Didn’t know about this medicine. Thanks for informing us about it. Blood pressure is a very common problem so any knowledge can be useful.

    • You’re welcome. I normally wouldn’t do a review of medicine but this was more about, does it work, but more importantly, if there were any side effects plus coming up with a plan with the doctor to get off of it.

  3. Hi.
    This will help those in search of blood pressure medications when they are travelling away from their country…also if you would give the generic name or may be names of those tablet with the same generic name…it would be better as in some countries you do not get the same name medicine.

    • Lisinopril is the generic form of the drug Zestril.

      That is a great comment though and I will update the post with this information. Thank you for stopping by and leaving a great comment.

  4. I took Lisinopril for a short time while I was experiencing some side effects from a steroid injection. My blood pressure kept rising and I was getting scared.
    Lisinopril worked but I had serious pain in my legs from using it. I quickly found natural products to stabilize my pressure. I checked my pressure regularly and tried to work with natural products. I changed the way I prepared my meals and the things I ate, I exercised and all was well.
    The doctor was satisfied and took me off I only had to monitor my blood pressure and report changes to him.
    The side effects of some medications are as dangerous as the symptoms you are taking them for. We have to help ourselves because a lot of the medications are KILLERS.
    Thanks for the reviews.

    • I couldn’t agree more with everything you said in your comments.

      I noticed yesterday and today while walking that my calves felt much more stiff. In the past I believe most of that was due to the cholesterol medicine but I’m going to have to keep a close watch on this.

      I am eating really clean with a lot more fruits, vegetables and healthy proteins. I’m about to go workout also. I am determined to get off this medication.

  5. I had been on lisinopril for years and just recently was changed to Losartan. My doctor said that Losartan has less side effects and is better for kidney function over a long period of time. I know that each doctor has their own preference as to which medicine they prefer. Mine told me that my BP issues were genetic and would probably be on them for the rest of my life. It might be worth it to ask your doctor about the difference between these to for your benefit. Thanks for the insight. Great information!!

    • I appreciate the feedback and letting me know about Losartan. I have a follow up doctor’s appointment and I hope to be off the medication at that point but if not, I will talk to my doctor about Losartan.

      Thank you.

  6. oh this is really interesting, thanks for sharing your experience.

    My dad suffers from high blood pressure and is always looking for a way to bring it down. I know diet and exercise is the best way to go but gosh we’ve tried that and cant make it do that.

    I guess other than that odd feeling, Lisinopril sounds like a good option. Will ask my dad to ask his doctor about it

    • It does work for me but I’m am working hard on the diet, exercise (and weight loss) to get off the medication. My weight is the number one thing that effects my blood pressure. I know my blood pressure will go down if all I do is lose weight.

      I hope your dad finds a way to control his blood pressure because it is one of the number one indicators of a risk of stroke. That’s what I found out after I had a stroke.

      Good Luck

  7. Hi Rick, a very informative post . My husband has high blood-pressure for many years, and he’s taking the medication (Metoprolol and Amlodipine. He’s okay with that.
    If you think having a high blood pressure is because the “stress”, then you may try some yoga, meditation or Qi Gong, have a massage.
    Your review has a nice presentation and nice documentation.
    Thank you.

    • Hi Jacqueline. I have had a few people mention yoga and meditation for stress and that is something I may end up doing.

      I keep my home and office conditions really relaxed plus I get out to the country and the mountains as much as possible. This helps me to keep my stress down a lot. I have also removed myself from stressful office situations with people that are difficult to work with and that is huge for me.

      I have been amazed as to how fast my blood pressure will jump with just one confrontation. I don’t have a problem with a majority of people but there are about 4 or 5 people that I do my best to not spend a lot of time around.


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